| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM570559 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Receptor Selection and Amplification (R-SAT) Assays |
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| Ki | 6.31±n/a nM |
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| Citation |  Burstein, ES; Olsson, R; Jansson, KE; Sköld, NP; Wahlström, LY; Borgström, BG; Von Wachenfeldt, H; Bergner, MG Compounds, salts thereof and methods for treatment of diseases US Patent US11440884 Publication Date 9/13/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A |
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| Type: | undefined |
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| Mol. Mass.: | 52607.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P28223 |
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| Residue: | 471 |
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| Sequence: | MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
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| BDBM570559 |
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| n/a |
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| Name | BDBM570559 |
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| Synonyms: | US11440884, Example 20 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H32F2N2O2 |
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| Mol. Mass. | 430.5306 |
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| SMILES | CC(C)COc1ccc(CC(=O)N(Cc2ccc(F)cc2)C2CCN(C)CC2)c(F)c1 |
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| Structure | 
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