| Reaction Details |
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 | Report a problem with these data |
| Target | Spike glycoprotein |
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| Ligand | BDBM571386 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Viral quantification via N-protein staining in New York |
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| IC50 | 700±n/a nM |
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| Citation |  Galan, A; Luo, W; Lal, R p38α mitogen-activated protein kinase inhibitors US Patent US11440918 Publication Date 9/13/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Spike glycoprotein |
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| Name: | Spike glycoprotein |
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| Synonyms: | E2 | Peplomer protein | S | S glycoprotein | SPIKE_SARS2 |
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| Type: | Protein |
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| Mol. Mass.: | 141178.35 |
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| Organism: | 2019-nCoV |
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| Description: | P0DTC2 |
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| Residue: | 1273 |
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| Sequence: | MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFS
NVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIV
NNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLE
GKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQT
LLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETK
CTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISN
CVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIAD
YNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPC
NGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVN
FNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITP
GTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSY
ECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTI
SVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQE
VFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDC
LGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAM
QMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALN
TLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRA
SANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPA
ICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDP
LQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDL
QELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDD
SEPVLKGVKLHYT
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| BDBM571386 |
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| n/a |
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| Name | BDBM571386 |
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| Synonyms: | N-(4-((1,4-oxazepan-4-yl)methyl)phenyl)-4-chlorobenzamide | US11440918, Compound 1 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21ClN2O2 |
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| Mol. Mass. | 344.835 |
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| SMILES | Clc1ccc(cc1)C(=O)Nc1ccc(CN2CCCOCC2)cc1 |
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| Structure | 
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