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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Transthyretin | ||
| Ligand | BDBM576396 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding of Examples to Transthyretin - EC50 Determination | ||
| EC50 | 31±n/a nM | ||
| Citation |  Shawn, C; Paul, CD; Lee, DR; Andrew, F; Magdalena, K; Yvette, LS; Timothy, LA; Vincent, M; Walter, PD; Andre, S; Mike, TM; Tao, W; Maria, WH (AZA)BENZOTHIAZOLYL SUBSTITUTED PYRAZOLE COMPOUNDS WIPOWO2022112919 Publication Date 6/2/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Transthyretin | |||
| Name: | Transthyretin | ||
| Synonyms: | ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 15884.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P02766 | ||
| Residue: | 147 | ||
| Sequence: |
| ||
| BDBM576396 | |||
| n/a | |||
| Name | BDBM576396 | ||
| Synonyms: | 4-(3,5-dimethyl-1H-pyrazol-4-yl)-1,3-benzothiazole | WO2022112919, Example 1 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C12H11N3S | ||
| Mol. Mass. | 229.301 | ||
| SMILES | Cc1n[nH]c(C)c1-c1cccc2scnc12 |(2.13,2.02,;2.13,.48,;3.37,-.43,;2.9,-1.89,;1.36,-1.89,;.45,-3.14,;.88,-.43,;-.59,.05,;-.91,1.55,;-2.37,2.03,;-3.51,1,;-3.19,-.51,;-4.1,-1.75,;-3.19,-3,;-1.73,-2.52,;-1.73,-.98,)| | ||
| Structure | 
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