Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Growth arrest-specific protein 6 | ||
Ligand | BDBM308338 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Activity Assay | ||
IC50 | 1.30±n/a nM | ||
Citation | Wang, X; Zhang, W; Frye, S Therapeutic uses of selected pyrimidine compounds with anti-Mer tyrosine kinase activity US Patent US9649309 Publication Date 5/16/2017 | ||
More Info.: | Get all data from this article, Assay Method | ||
Growth arrest-specific protein 6 | |||
Name: | Growth arrest-specific protein 6 | ||
Synonyms: | AXL receptor tyrosine kinase ligand | AXLLG | GAS-6 | GAS6 | GAS6_HUMAN | ||
Type: | PROTEIN | ||
Mol. Mass.: | 74914.43 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q14393 | ||
Residue: | 678 | ||
Sequence: |
| ||
BDBM308338 | |||
n/a | |||
Name | BDBM308338 | ||
Synonyms: | US9649309, Compound UNC4247A | ||
Type | Small organic molecule | ||
Emp. Form. | C26H31FN6O | ||
Mol. Mass. | 462.5623 | ||
SMILES | O[C@H]1CC[C@@H](CC1)Nc1nc(Nc2cccc(F)c2)ncc1-c1ccc(CN2CCCC2)cn1 |r,wU:4.7,wD:1.0,(-6.52,3.85,;-5.19,3.08,;-5.19,1.54,;-3.85,.77,;-2.52,1.54,;-2.52,3.08,;-3.85,3.85,;-1.18,.77,;-1.18,-.77,;-2.52,-1.54,;-2.52,-3.08,;-3.85,-3.85,;-5.19,-3.08,;-5.19,-1.54,;-6.52,-.77,;-7.85,-1.54,;-7.85,-3.08,;-9.19,-3.85,;-6.52,-3.85,;-1.18,-3.85,;.15,-3.08,;.15,-1.54,;1.48,-.77,;2.82,-1.54,;4.15,-.77,;4.15,.77,;5.48,1.54,;6.82,.77,;6.82,-.77,;8.28,-1.25,;9.19,,;8.28,1.25,;2.82,1.54,;1.48,.77,)| | ||
Structure |