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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Growth arrest-specific protein 6 | ||
| Ligand | BDBM308339 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Activity Assay | ||
| IC50 | 3.60±n/a nM | ||
| Citation |  Wang, X; Zhang, W; Frye, S Therapeutic uses of selected pyrimidine compounds with anti-Mer tyrosine kinase activity US Patent US9649309 Publication Date 5/16/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Growth arrest-specific protein 6 | |||
| Name: | Growth arrest-specific protein 6 | ||
| Synonyms: | AXL receptor tyrosine kinase ligand | AXLLG | GAS-6 | GAS6 | GAS6_HUMAN | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 74914.43 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q14393 | ||
| Residue: | 678 | ||
| Sequence: |
| ||
| BDBM308339 | |||
| n/a | |||
| Name | BDBM308339 | ||
| Synonyms: | US9649309, Compound UNC4372A | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H31N7O | ||
| Mol. Mass. | 469.5813 | ||
| SMILES | O[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(cc2)[N+]#[C-])ncc1-c1ccc(CN2CCCC2)cn1 |r,wU:4.7,wD:1.0,(-5.85,3.85,;-4.52,3.08,;-4.52,1.54,;-3.19,.77,;-1.85,1.54,;-1.85,3.08,;-3.19,3.85,;-.52,.77,;-.52,-.77,;-1.85,-1.54,;-1.85,-3.08,;-3.19,-3.85,;-4.52,-3.08,;-5.85,-3.85,;-7.19,-3.08,;-7.25,-1.46,;-5.85,-.77,;-4.52,-1.54,;-8.57,-.67,;-9.9,.11,;-.52,-3.85,;.82,-3.08,;.82,-1.54,;2.15,-.77,;3.48,-1.54,;4.82,-.77,;4.82,.77,;6.15,1.54,;7.48,.77,;7.48,-.77,;8.95,-1.25,;9.85,,;8.95,1.25,;3.48,1.54,;2.15,.77,)| | ||
| Structure | 
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