| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM158073 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibitory Activity Assay |
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| Ki | 0.610±n/a nM |
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| Citation |  Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Heteroarylcarboxylic acid ester derivative US Patent US9655879 Publication Date 5/23/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26557.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07477 |
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| Residue: | 247 |
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| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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| BDBM158073 |
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| n/a |
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| Name | BDBM158073 |
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| Synonyms: | US9024044, 1 | US9227949, 1 | US9655879, 1 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22FN3O7S |
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| Mol. Mass. | 491.489 |
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| SMILES | NC(=N)c1ccc(OC(=O)c2ccc(CC3(CCC3)C(=O)N[C@@H](CC(O)=O)C(O)=O)s2)c(F)c1 |r| |
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| Structure | 
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