| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Enteropeptidase |
|---|
| Ligand | BDBM158131 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibitory Activity Assay |
|---|
| Ki | 0.310±n/a nM |
|---|
| Citation |  Koshiba, T; Tokumasu, M; Ichimaru, T; Ohsumi, K; Nakagawa, T; Yamada, T; Matsumoto, K; Suzuki, T Heteroarylcarboxylic acid ester derivative US Patent US9655879 Publication Date 5/23/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Enteropeptidase |
|---|
| Name: | Enteropeptidase |
|---|
| Synonyms: | ENTK | ENTK_HUMAN | PRSS7 | TMPRSS15 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 112901.62 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P98073 |
|---|
| Residue: | 1019 |
|---|
| Sequence: | MGSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARA
TFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSII
VVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNV
SIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQA
THYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETN
PGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDL
NDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEP
ACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFN
AFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSST
NFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPG
PVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVN
LCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLG
LGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQD
ITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAI
LGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEE
NQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYE
EGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQSFLH
|
|
|
|---|
| BDBM158131 |
|---|
| n/a |
|---|
| Name | BDBM158131 |
|---|
| Synonyms: | US9024044, 59 | US9227949, 59 | US9655879, 59 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H22FN3O7S |
|---|
| Mol. Mass. | 527.521 |
|---|
| SMILES | CC(C)(Cc1ccc(s1)C(=O)Oc1ccc(cc1F)C(N)=N)C(=O)Nc1cc(cc(c1)C(O)=O)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
