| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor [N127C] |
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| Ligand | BDBM579538 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Binding Assay |
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| Ki | 4.10±n/a nM |
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| Citation |  Shoichet, BK; Lin, H; Gmeiner, P; Manglik, A; Kobilka, B; Roth, BL; Dengler, DG Mu opioid receptor modulators US Patent US11484525 Publication Date 11/1/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor [N127C] |
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| Name: | Mu-type opioid receptor [N127C] |
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| Synonyms: | MOR1 | OPRM1 | OPRM_HUMAN |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44778.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 [N127C] |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVCYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM579538 |
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| n/a |
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| Name | BDBM579538 |
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| Synonyms: | US11484525, Compound BD-131LR |
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| Type | Small organic molecule |
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| Emp. Form. | C21H31N3O2S |
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| Mol. Mass. | 389.555 |
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| SMILES | CC(Cc1ccsc1)NC(=O)NC[C@H](Cc1c(C)cc(O)cc1C)N(C)C |r| |
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| Structure | 
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