| Reaction Details |
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 | Report a problem with these data |
| Target | Synaptic vesicle glycoprotein 2A |
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| Ligand | BDBM582019 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Radioligand Competition Binding Assay |
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| IC50 | 12.6±n/a nM |
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| Citation |  Huang, Y; Cai, Z; Li, S; Nabulsi, N; Carson, R Radiolabeled pharmaceuticals and methods of making and using same US Patent US11518754 Publication Date 12/6/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Synaptic vesicle glycoprotein 2A |
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| Name: | Synaptic vesicle glycoprotein 2A |
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| Synonyms: | SV2A_RAT | Sv2 | Sv2a | Synaptic vesicle protein 2a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 82648.76 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_100153 |
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| Residue: | 742 |
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| Sequence: | MEEGFRDRAAFIRGAKDIAKEVKKHAAKKVVKGLDRVQDEYSRRSYSRFEEEEDDDDFPA
PADGYYRGEGAQDEEEGGASSDATEGHDEDDEIYEGEYQGIPRAESGGKGERMADGAPLA
GVRGGLSDGEGPPGGRGEAQRRKDREELAQQYETILRECGHGRFQWTLYFVLGLALMADG
VEVFVVGFVLPSAEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLS
VNSVFAFFSSFVQGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFW
MIGGVYAAAMAWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRF
FLENGKHDEAWMVLKQVHDTNMRAKGHPERVFSVTHIKTIHQEDELIEIQSDTGTWYQRW
GVRALSLGGQVWGNFLSCFSPEYRRITLMMMGVWFTMSFSYYGLTVWFPDMIRHLQAVDY
AARTKVFPGERVEHVTFNFTLENQIHRGGQYFNDKFIGLRLKSVSFEDSLFEECYFEDVT
SSNTFFRNCTFINTVFYNTDLFEYKFVNSRLVNSTFLHNKEGCPLDVTGTGEGAYMVYFV
SFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVLSCVSCFFLSFGNSESAMIALLCLFGG
VSIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVGITKAAPILFAS
AALALGSSLALKLPETRGQVLQ
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| BDBM582019 |
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| n/a |
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| Name | BDBM582019 |
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| Synonyms: | US11518754, Compound (R)-4 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H16F2N2O |
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| Mol. Mass. | 302.3185 |
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| SMILES | Cc1cnccc1CN1C[C@H](CC1=O)c1ccc(F)c(F)c1 |r| |
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| Structure | 
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