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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Potassium channel subfamily K member 2 | ||
| Ligand | BDBM610740 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | LMPTP Primary Screening Protocol | ||
| IC50 | 500±n/a nM | ||
| Citation |  Bottini, N; Zou, J; Ganji, SR; Stanford, S; Pinkerton, A; Chung, TD; Hedrick, M; Ardecky, R Inhibitors of low molecular weight protein tyrosine phosphatase and uses thereof US Patent US10626094 Publication Date 4/21/2020 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Potassium channel subfamily K member 2 | |||
| Name: | Potassium channel subfamily K member 2 | ||
| Synonyms: | KCNK2 | KCNK2_HUMAN | Outward rectifying potassium channel protein TREK-1 | TREK | TREK-1 K(+) channel subunit | TREK1 | Twik-RElated Potassium (K+) channel 1 (TREK1) | Two pore domain potassium channel TREK-1 | Two pore potassium channel TPKC1 | ||
| Type: | Protein | ||
| Mol. Mass.: | 47099.16 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O95069 | ||
| Residue: | 426 | ||
| Sequence: |
| ||
| BDBM610740 | |||
| n/a | |||
| Name | BDBM610740 | ||
| Synonyms: | 2-[(4-methoxyphenyl)(4-quinolyl)][3- (pyrrolidinylmethyl)phenyl]amine | US10626094, Example G51 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H27N3O | ||
| Mol. Mass. | 409.5228 | ||
| SMILES | COc1ccc(cc1)-c1cc(-c2c(N)cccc2CN2CCCC2)c2ccccc2n1 |(-5.33,1.54,;-4,2.31,;-2.67,1.54,;-2.67,,;-1.33,-.77,;;,1.54,;-1.33,2.31,;1.33,-.77,;1.33,-2.31,;2.67,-3.08,;2.67,-4.62,;4,-5.39,;5.33,-4.62,;4,-6.93,;2.67,-7.7,;1.33,-6.93,;1.33,-5.39,;,-4.62,;-1.33,-5.39,;-1.49,-6.92,;-3,-7.24,;-3.77,-5.91,;-2.74,-4.76,;4,-2.31,;5.33,-3.08,;6.67,-2.31,;6.67,-.77,;5.33,,;4,-.77,;2.67,,)| | ||
| Structure | 
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