| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM616097 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Adenosine Receptor Binding Assay |
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| Ki | 0.200±n/a nM |
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| Citation |  Brown, GA; Richardson, CM; Congreve, MS; Paul, R; Andrews, SP; Mason, JS 5-AMINO-8-(4-PYRIDYL)-[1,2,4]TRIAZOLO[4,3-C]PYRIMIDIN-3-ONE COMPOUNDS FOR USE AGAINST CANCER US Patent US20230271964 Publication Date 8/31/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM616097 |
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| n/a |
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| Name | BDBM616097 |
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| Synonyms: | US20230271964, Example 1-54 | US20230271964, Example 1-57 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H18ClN7O3 |
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| Mol. Mass. | 463.876 |
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| SMILES | Cc1ocnc1Cn1nc2c(-c3cc(Cl)nc(CO)c3)c(nc(N)n2c1=O)-c1ccccc1 |
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| Structure | 
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