| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase I isoform delta |
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| Ligand | BDBM629089 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Assay |
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| IC50 | 1066±n/a nM |
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| Citation |  Lebold, TP; McCarver, S; McClure, KJ; Preville, C; Seierstad, M; Shireman, BT; Wang, J; Wu, D; Zhang, W; Ziff, JM CASEIN KINASE 1 DELTA MODULATORS US Patent US20230339900 Publication Date 10/26/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Casein kinase I isoform delta |
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| Name: | Casein kinase I isoform delta |
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| Synonyms: | CKI-delta | CKId | CSNK1D | Casein kinase 1 delta (CK1δ) | Casein kinase I delta | Casein kinase I isoform alpha/delta | Casein kinase I isoform delta (CK1D) | HCKID | KC1D_HUMAN | casein kinases 1 delta (CK1 delta) |
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| Type: | Enzyme |
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| Mol. Mass.: | 47356.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48730 |
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| Residue: | 415 |
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| Sequence: | MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
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| BDBM629089 |
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| n/a |
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| Name | BDBM629089 |
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| Synonyms: | 4-(1-(Difluoromethyl)-3-(5-fluoropyridin-2-yl)-1H-pyrazol-4-yl)-1H- | US20230339900, Example 66 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H9F3N6 |
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| Mol. Mass. | 330.2674 |
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| SMILES | FC(F)n1cc(c(n1)-c1ccc(F)cn1)-c1ccnc2[nH]ncc12 |
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| Structure | 
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