BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetBiofilm regulatory protein A
LigandBDBM643904
Substrate/Competitorn/a
Meas. Tech.Inhibition of the activity of Gtfs determined by Zymographic Assay
IC50 38800±n/a nM
Citation Velu, SEWu, HZhang, QNijampatnam, B Streptococcus mutans glucosyl transferase inhibitors for dental caries therapy US Patent US11866416 Publication Date 1/9/2024
More Info.:Get all data from this article,  Assay Method
 
Biofilm regulatory protein A
Name:Biofilm regulatory protein A
Synonyms:n/a
Type:Protein
Mol. Mass.:43911.21
Organism:Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Description:Q8DVR0
Residue:406
Sequence:
MKIGKKILIMLVTIFLTSLVALGVYATSIYNFSLGEFSKTFKDYGTGSGKDVIADEKPFS
ILLMGVDTGSSERTSKWEGNSDSMILVTVNPKTKKTTMTSLERDILVKLSGSKTNDQTGY
DAKLNAAYAAGGAKMAIMTVQDMLDIKIDKYVQINMEGLVQLVDAVGGITVTNHFDFPIS
IEEHEPEFTASVEPGTHKINGEQALVYSRMRYDDPDGDYGRQKRQREVISKVLKKILALD
SVSKYRKILSAVSKNMQTNIEISSSTIPKLLGYSDALKSIRTYQLKGEGTTIDGGSYQLV
TSKELLKAQNRIKGQLGLKKSTAENLKTTASLYENFYGGDTSIYDSSSSASDYSSSGNYS
GSSSDYGSSSSYGSNSSSGSSSDYSGQNSYNQGNYQQPAAGTGIGN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM643904
n/a
NameBDBM643904
Synonyms:US11866416, Compound SN-I-235D | US11866416, Compound SN-I-235d
TypeSmall organic molecule
Emp. Form.C16H11N3O5
Mol. Mass.325.2756
SMILESNC(=O)c1cccc(NC(=O)c2cc3cc(ccc3o2)[N+]([O-])=O)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: