| Reaction Details |
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 | Report a problem with these data |
| Target | Biofilm regulatory protein A |
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| Ligand | BDBM644004 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition of the activity of Gtfs determined by Zymographic Assay |
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| IC50 | 23400±n/a nM |
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| Citation |  Velu, SE; Wu, H; Zhang, Q; Nijampatnam, B Streptococcus mutans glucosyl transferase inhibitors for dental caries therapy US Patent US11866416 Publication Date 1/9/2024 |
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| More Info.: | Get all data from this article, Assay Method |
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| Biofilm regulatory protein A |
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| Name: | Biofilm regulatory protein A |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 43911.21 |
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| Organism: | Streptococcus mutans serotype c (strain ATCC 700610 / UA159) |
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| Description: | Q8DVR0 |
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| Residue: | 406 |
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| Sequence: | MKIGKKILIMLVTIFLTSLVALGVYATSIYNFSLGEFSKTFKDYGTGSGKDVIADEKPFS
ILLMGVDTGSSERTSKWEGNSDSMILVTVNPKTKKTTMTSLERDILVKLSGSKTNDQTGY
DAKLNAAYAAGGAKMAIMTVQDMLDIKIDKYVQINMEGLVQLVDAVGGITVTNHFDFPIS
IEEHEPEFTASVEPGTHKINGEQALVYSRMRYDDPDGDYGRQKRQREVISKVLKKILALD
SVSKYRKILSAVSKNMQTNIEISSSTIPKLLGYSDALKSIRTYQLKGEGTTIDGGSYQLV
TSKELLKAQNRIKGQLGLKKSTAENLKTTASLYENFYGGDTSIYDSSSSASDYSSSGNYS
GSSSDYGSSSSYGSNSSSGSSSDYSGQNSYNQGNYQQPAAGTGIGN
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| BDBM644004 |
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| n/a |
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| Name | BDBM644004 |
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| Synonyms: | US11866416, Compound SN-II-59 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H10N4O6S |
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| Mol. Mass. | 386.339 |
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| SMILES | NC(=O)c1cc(NC(=O)c2cc3cc(ccc3s2)[N+]([O-])=O)ccc1[N+]([O-])=O |
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| Structure | 
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