| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM524544 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | A2B Filter Binding Assay |
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| EC50 | <10±n/a nM |
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| Citation |  Wang, X; Han, H; McCammant, MS; Wu, L; Yao, W; Yu, Z; Zhao, L Fused pyrimidine derivatives as A2A/A2B inhibitors US Patent US11873304 Publication Date 1/16/2024 |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM524544 |
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| n/a |
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| Name | BDBM524544 |
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| Synonyms: | US11168089, Ex. No. 20 | US11873304, Example 20 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H19F2N7O2 |
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| Mol. Mass. | 475.4502 |
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| SMILES | Nc1nc(cc2nc(Cc3c(F)cccc3CN[C@@H]3CCOC3=O)nn12)-c1cccc(C#N)c1F |r| |
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| Structure | 
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