| Reaction Details |
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 | Report a problem with these data |
| Target | Macrophage migration inhibitory factor |
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| Ligand | BDBM648260 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | MIF Enzymatic Assay |
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| IC50 | 18.6±n/a nM |
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| Citation |  Fan, G; Fong, KC; Yang, H; Wang, J Compounds and their uses as MIF inhibitors US Patent US11884682 Publication Date 1/30/2024 |
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| More Info.: | Get all data from this article, Assay Method |
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| Macrophage migration inhibitory factor |
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| Name: | Macrophage migration inhibitory factor |
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| Synonyms: | GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase |
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| Type: | Enzyme |
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| Mol. Mass.: | 12478.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14174 |
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| Residue: | 115 |
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| Sequence: | MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
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| BDBM648260 |
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| n/a |
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| Name | BDBM648260 |
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| Synonyms: | 2,4-dimethoxy-N-(5-(thiophen-3-yl)- 1,3,4-oxadiazol-2-yl)benzamide | US11884682, Compound 5 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H13N3O4S |
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| Mol. Mass. | 331.346 |
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| SMILES | COc1ccc(C(=O)Nc2nnc(o2)-c2ccsc2)c(OC)c1 |
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| Structure | 
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