| Reaction Details |
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 | Report a problem with these data |
| Target | Steroid hormone receptor ERR1 |
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| Ligand | BDBM312096 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Competitive Radioligand-Binding Assay |
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| Ki | 32.0±n/a nM |
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| Citation |  Narayanan, R; Dalton, JT; Levin, E Nuclear receptor binding agents US Patent US9604931 Publication Date 3/28/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Steroid hormone receptor ERR1 |
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| Name: | Steroid hormone receptor ERR1 |
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| Synonyms: | ERR-alpha | ERR1 | ERR1_HUMAN | ESRL1 | ESRRA | Estrogen receptor-like 1 | Estrogen-Related Receptor, alpha | Estrogen-related receptor alpha | NR3B1 | Nuclear receptor subfamily 3 group B member 1 | Steroid hormone receptor ERR1 | Steroid hormone receptor ERR1 alpha | Steroid hormone receptor ERR1/Estrogen-related receptor alpha (ERRa) | von Hippel-Lindau disease tumor suppressor/Steroid hormone receptor ERR1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45508.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1499891 |
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| Residue: | 423 |
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| Sequence: | MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAG
PGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNE
CEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGP
LAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTI
SWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAA
GLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALL
EYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEA
MMD
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|
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| BDBM312096 |
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| n/a |
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| Name | BDBM312096 |
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| Synonyms: | 4-bromo-6,8-dihydroxy-2-(4-hydroxyphenyl)isoquinolin-1(2H)-one | US9604931, 12u | US9623021, Compound 12u |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10BrNO4 |
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| Mol. Mass. | 348.148 |
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| SMILES | Oc1ccc(cc1)-n1cc(Br)c2cc(O)cc(O)c2c1=O |
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| Structure | 
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