| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Steroid hormone receptor ERR2 |
|---|
| Ligand | BDBM312139 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Competitive Radioligand-Binding Assay |
|---|
| Ki | 3.96±n/a nM |
|---|
| Citation |  Narayanan, R; Dalton, JT; Levin, E Nuclear receptor binding agents US Patent US9604931 Publication Date 3/28/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Steroid hormone receptor ERR2 |
|---|
| Name: | Steroid hormone receptor ERR2 |
|---|
| Synonyms: | ERR beta-2 | ERR-beta | ERR2_HUMAN | ERRB2 | ESRL2 | ESRRB | Estrogen receptor-like 2 | Estrogen-related receptor beta | NR3B2 | Nuclear receptor subfamily 3 group B member 2 | Steroid hormone receptor ERR2 | Steroid hormone receptor ERR2 Beta |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 48061.77 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_11254 |
|---|
| Residue: | 433 |
|---|
| Sequence: | MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP
MFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASC
EACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRG
GRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKAL
TTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLV
YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL
EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP
MHKLFLEMLEAKV
|
|
|
|---|
| BDBM312139 |
|---|
| n/a |
|---|
| Name | BDBM312139 |
|---|
| Synonyms: | 2-(3-fluoro-4-hydroxyphenyl)-6,8-dihydroxy-4-vinylisoquinolin-1(2H)-one | US9604931, 15c | US9623021, Compound 15c |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H12FNO4 |
|---|
| Mol. Mass. | 313.2799 |
|---|
| SMILES | Oc1cc(O)c2c(c1)c(C=C)cn(-c1ccc(O)c(F)c1)c2=O |
|---|
| Structure | 
|
|---|
Search and Browse
