| Reaction Details |
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 | Report a problem with these data |
| Target | Steroid hormone receptor ERR2 |
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| Ligand | BDBM312140 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Competitive Radioligand-Binding Assay |
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| Ki | 0.480±n/a nM |
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| Citation |  Narayanan, R; Dalton, JT; Levin, E Nuclear receptor binding agents US Patent US9604931 Publication Date 3/28/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Steroid hormone receptor ERR2 |
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| Name: | Steroid hormone receptor ERR2 |
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| Synonyms: | ERR beta-2 | ERR-beta | ERR2_HUMAN | ERRB2 | ESRL2 | ESRRB | Estrogen receptor-like 2 | Estrogen-related receptor beta | NR3B2 | Nuclear receptor subfamily 3 group B member 2 | Steroid hormone receptor ERR2 | Steroid hormone receptor ERR2 Beta |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48061.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_11254 |
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| Residue: | 433 |
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| Sequence: | MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP
MFAGAGLGGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASC
EACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRG
GRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKAL
TTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLV
YAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDL
EAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVP
MHKLFLEMLEAKV
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| BDBM312140 |
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| n/a |
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| Name | BDBM312140 |
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| Synonyms: | 6,8-dihydroxy-2-(4-hydroxyphenyl)-4-(4-methoxyphenyl)isoquinolin-1(2H)-one | 6,8-dihydroxy-2-(4-hydroxyphenyl)-4-phenylisoquinolin-1(2H)-one | US9604931, 15g | US9623021, Compound 15g |
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| Type | Small organic molecule |
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| Emp. Form. | C22H17NO5 |
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| Mol. Mass. | 375.3741 |
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| SMILES | COc1ccc(cc1)-c1cn(-c2ccc(O)cc2)c(=O)c2c(O)cc(O)cc12 |
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| Structure | 
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