| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Caspase-6 |
|---|
| Ligand | BDBM10351 |
|---|
| Substrate/Competitor | Caspase-6 Fluorogenic Substrate |
|---|
| Meas. Tech. | Caspase Inhibition Assay |
|---|
| IC50 | >5000±n/a nM |
|---|
| Citation |  Chu, W; Zhang, J; Zeng, C; Rothfuss, J; Tu, Z; Chu, Y; Reichert, DE; Welch, MJ; Mach, RH N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies. J Med Chem48:7637-47 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Caspase-6 |
|---|
| Name: | Caspase-6 |
|---|
| Synonyms: | Apoptotic protease Mch-2 | CASP-6 | CASP6 | CASP6_HUMAN | Caspase | MCH2 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 33312.62 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P55212 |
|---|
| Residue: | 293 |
|---|
| Sequence: | MSSASGLRRGHPAGGEENMTETDAFYKREMFDPAEKYKMDHRRRGIALIFNHERFFWHLT
LPERRGTCADRDNLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVSHADADCFVCVFLS
HGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHDVPVIPLDVVDN
QTEKLDTNITEVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKYG
SSLEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQVPCFASMLTKKLHFFPKSN
|
|
|
|---|
| BDBM10351 |
|---|
| Caspase-6 Fluorogenic Substrate |
|---|
| Name: | Caspase-6 Fluorogenic Substrate |
|---|
| Synonyms: | Ac-VEID-AMC |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 1560.92 |
|---|
| Organism: | n/a |
|---|
| Description: | AMC=7-Amino-4-methylcoumarin |
|---|
| Residue: | 16 |
|---|
| Sequence: | |
|---|
Search and Browse
