| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP4 subtype |
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| Ligand | BDBM204989 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Receptor Binding Assay |
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| IC50 | >300±0 nM |
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| Citation |  Feutrill, J; Leriche, C; Middlemiss, D Aniline derivatives, their preparation and their therapeutic application US Patent US9624159 Publication Date 4/18/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP4 subtype |
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| Name: | Prostaglandin E2 receptor EP4 subtype |
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| Synonyms: | PE2R4_HUMAN | PGE receptor EP4 subtype | PGE2 receptor EP4 subtype | PTGER2 | PTGER4 | Prostaglandin E2 receptor | Prostanoid EP4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 53134.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35408 |
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| Residue: | 488 |
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| Sequence: | MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP
SLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSG
QHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPG
MGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSET
LNLSEKCI
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| BDBM204989 |
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| n/a |
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| Name | BDBM204989 |
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| Synonyms: | US9249085, I(aw) | US9624159, Compound I(aw) |
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| Type | Small organic molecule |
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| Emp. Form. | C24H23F2NO3 |
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| Mol. Mass. | 411.4411 |
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| SMILES | Cc1ccc(OCC(O)=O)c(C)c1NCc1cc(cc(F)c1C)-c1cccc(F)c1 |
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| Structure | 
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