| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin F2-alpha receptor |
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| Ligand | BDBM323766 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Test of Inhibition of Human FP Receptor Activity (B-1A) |
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| IC50 | 140±n/a nM |
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| Citation |  Beck, H; Thaler, T; Kast, R; Meibom, D; Meininghaus, M; Terjung, C; Delbeck, M; Lustig, K; Muenster, U; Olenik, B Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents US Patent US10189788 Publication Date 1/29/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin F2-alpha receptor |
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| Name: | Prostaglandin F2-alpha receptor |
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| Synonyms: | PF2R_HUMAN | PGF receptor | PGF2 alpha receptor | PGF2-alpha receptor | PTGFR | Prostaglandin F | Prostanoid FP receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40072.29 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43088 |
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| Residue: | 359 |
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| Sequence: | MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ
KSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGL
CPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQ
ASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG
RSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILD
PWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
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| BDBM323766 |
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| n/a |
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| Name | BDBM323766 |
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| Synonyms: | 4-({[6-Bromo-3-methyl-2-(pyridin-4-yl)quinolin-4-yl]carbonyl}amino)-3-fluorobenzoic acid | US10189788, Example 46 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H15BrFN3O3 |
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| Mol. Mass. | 480.286 |
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| SMILES | Cc1c(nc2ccc(Br)cc2c1C(=O)Nc1ccc(cc1F)C(O)=O)-c1ccncc1 |
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| Structure | 
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