| Reaction Details |
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 | Report a problem with these data |
| Target | Orexin receptor type 2 |
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| Ligand | BDBM163898 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Human Orexin 2 Receptor Radioligand Binding Assay |
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| Ki | 60.0±n/a nM |
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| Citation |  Coate, HR; Dvorak, CA; Fitzgerald, AE; Lebold, TP; Preville, C; Shireman, BT Substituted 7-azabicycles and their use as orexin receptor modulators US Patent US9637496 Publication Date 5/2/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Orexin receptor type 2 |
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| Name: | Orexin receptor type 2 |
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| Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R |
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| Type: | Protein |
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| Mol. Mass.: | 50710.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O43614 |
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| Residue: | 444 |
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| Sequence: | MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR
KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN
PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL
SEQVVLTSISTLPAANGAGPLQNW
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| BDBM163898 |
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| n/a |
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| Name | BDBM163898 |
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| Synonyms: | US9062078, 29 | US9475819, 29 | US9637496, 29 | US9695183, 29 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H21F2N3O2S |
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| Mol. Mass. | 441.494 |
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| SMILES | Cc1nc(C(=O)N2C3CCC2C(COc2ccc(F)cn2)C3)c(s1)-c1ccccc1F |TLB:12:11:9.8:6| |
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| Structure | 
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