| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
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| Ligand | BDBM193818 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Receptor Selection and Amplification Assays |
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| EC50 | 63±n/a nM |
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| Citation |  Burstein, ES; Eskildsen, J; Olsson, R Muscarinic agonists US Patent US9670209 Publication Date 6/6/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M2 |
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| Name: | Muscarinic acetylcholine receptor M2 |
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| Synonyms: | ACM2_HUMAN | CHRM2 | Cholinergic, muscarinic M2 | Muscarinic acetylcholine receptor M2 and M4 | Muscarinic acetylcholine receptor M2 and M5 | RecName: Full=Muscarinic acetylcholine receptor M2 |
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| Type: | GPCR |
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| Mol. Mass.: | 51730.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08172 |
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| Residue: | 466 |
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| Sequence: | MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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| BDBM193818 |
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| n/a |
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| Name | BDBM193818 |
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| Synonyms: | US9670209, Compound 320 1-((R)-3-((1R,3R,58)-3-(2-methoxyethylidene)-8-azabicyclo[3.2.1]octan-8-yl)-2-methylpropyl)-1H-indazole |
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| Type | Small organic molecule |
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| Emp. Form. | C21H29N3O |
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| Mol. Mass. | 339.4745 |
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| SMILES | COC\C=C1\C[C@@H]2CC[C@H](C1)N2C[C@@H](C)Cn1ncc2ccccc12 |r,THB:12:11:10.4.5:7.8| |
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| Structure | 
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