| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 4 |
|---|
| Ligand | BDBM327448 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Competition Assay |
|---|
| Ki | 3.80±n/a nM |
|---|
| Citation |  Dallemagne, P; Rochais, C; Lecoutey, C; Boulouard, M; Freret, T Acetylcholinesterase inhibitors and promnesiant serotonin 5-HT4 receptor agonists, their methods of preparation and the pharmaceutical compositions containing the same US Patent US9663465 Publication Date 5/30/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 4 |
|---|
| Name: | 5-hydroxytryptamine receptor 4 |
|---|
| Synonyms: | 5-HT-4 | 5-HT4 | 5-HT4S | 5-HT4a | 5-HT4b | 5-HT4c | 5-HT4d | 5-HT4hb | 5-hydroxytryptamine receptor 4 | 5-hydroxytryptamine receptor 4 (5-HT4) | 5HT4R_HUMAN | HTR4 | Serotonin (5-HT) receptor | Serotonin (5-HT3) receptor | Serotonin 4 (5-HT4) receptor | Serotonin Receptor 4 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 43767.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q13639 |
|---|
| Residue: | 388 |
|---|
| Sequence: | MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD
AVECGGQWESQCHPPATSPLVAAQPSDT
|
|
|
|---|
| BDBM327448 |
|---|
| n/a |
|---|
| Name | BDBM327448 |
|---|
| Synonyms: | 1-(4-amino-5-fluoro-2-methoxyphenyl)-3-[1-(cyclohexylmethyl)-4-piperidyl]propan-1-one | US9663465, 5 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H33FN2O2 |
|---|
| Mol. Mass. | 376.508 |
|---|
| SMILES | COc1cc(N)c(F)cc1C(=O)CCC1CCN(CC2CCCCC2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
