| Reaction Details |
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 | Report a problem with these data |
| Target | Isoform Beta of cGMP-dependent protein kinase 1 [1-351] |
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| Ligand | BDBM65505 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Microfluidic Mobility-Shift Assay |
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| pH | 7±n/a |
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| EC50 | 3.8±0.4 nM |
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| Comments | extracted |
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| Citation |  Campbell, JC; Henning, P; Franz, E; Sankaran, B; Herberg, FW; Kim, C Structural Basis of Analog Specificity in PKG I and II. ACS Chem Biol12:2388-2398 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Isoform Beta of cGMP-dependent protein kinase 1 [1-351] |
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| Name: | Isoform Beta of cGMP-dependent protein kinase 1 [1-351] |
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| Synonyms: | KGP1_HUMAN | PRKG1 | PRKG1B | PRKGR1A | PRKGR1B | cGMP-dependent protein kinase 1 [1-351] | hPKG 1 beta (aa 1-351) |
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| Type: | Protein |
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| Mol. Mass.: | 39673.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13976-2 (1-351) |
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| Residue: | 351 |
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| Sequence: | MGTLRDLQYALQEKIEELRQRDALIDELELELDQKDELIQKLQNELDKYRSVIRPATQQA
QKQSASTLQGEPRTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMK
NLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKV
FGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSL
PEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLG
KGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAY
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| BDBM65505 |
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| n/a |
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| Name | BDBM65505 |
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| Synonyms: | PET-cGMP |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16N5O7P |
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| Mol. Mass. | 445.3227 |
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| SMILES | O[C@@H]1[C@@H]2OP(O)(=O)OC[C@H]2O[C@H]1n1cnc2c1[nH]c1nc(cn1c2=O)-c1ccccc1 |
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| Structure | 
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