| Reaction Details |
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 | Report a problem with these data |
| Target | Histone H3.1 |
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| Ligand | BDBM50248522 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Histone H3 Acetylation Assay |
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| EC50 | 500±n/a nM |
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| Citation |  Chen, D; Song, HY; Sun, ET; Yu, N; Zou, Y Benzimidazole derivatives: preparation and pharmaceutical applications US Patent US10201527 Publication Date 2/12/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone H3.1 |
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| Name: | Histone H3.1 |
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| Synonyms: | H31_HUMAN | H3C1 | H3FA | H3FB | H3FC HIST1H3C | H3FD | H3FF | H3FH | H3FI | H3FJ | H3FK | H3FL | HIST1H3A | HIST1H3B | HIST1H3D | HIST1H3E | HIST1H3F | HIST1H3G | HIST1H3H | HIST1H3I | HIST1H3J |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 15425.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 136 |
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| Sequence: | MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTE
LLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTI
MPKDIQLARRIRGERA
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|
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| BDBM50248522 |
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| n/a |
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| Name | BDBM50248522 |
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| Synonyms: | CHEMBL489332 | N-hydroxy-3-(2-phenethyl-1-(2-(piperidin-1-yl)ethyl)-1H-benzo[d]imidazol-5-yl)acrylamide | US10201527, Compound 67 | US10736881, Compound 67 | US8551988, 67 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H30N4O2 |
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| Mol. Mass. | 418.5313 |
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| SMILES | ONC(=O)\C=C\c1ccc2n(CCN3CCCCC3)c(CCc3ccccc3)nc2c1 |
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| Structure | 
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