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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sodium channel protein type 9 subunit alpha | ||
| Ligand | BDBM145327 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Electrophysiological Assay (In Vitro Assay) | ||
| IC50 | 84.7±n/a nM | ||
| Citation |  Chowdhury, S; Dehnhardt, CM; Focken, T; Grimwood, ME; Hemeon, IW; Jia, Q; Ortwine, DF; Safina, B; Sun, S; Sutherlin, DP; Zenova, AY N-substituted benzamides and methods of use thereof US Patent US9771376 Publication Date 9/26/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Sodium channel protein type 9 subunit alpha | |||
| Name: | Sodium channel protein type 9 subunit alpha | ||
| Synonyms: | NENA | Neuroendocrine sodium channel | Peripheral sodium channel 1 | SCN9A | SCN9A_HUMAN | Sodium channel protein type IX alpha subunit | Voltage-gated sodium channel subunit Nav1.7 | Voltage-gated sodium channel subunit alpha Nav1.7 | hNE-Na | ||
| Type: | Protein | ||
| Mol. Mass.: | 226375.97 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15858 | ||
| Residue: | 1988 | ||
| Sequence: |
| ||
| BDBM145327 | |||
| n/a | |||
| Name | BDBM145327 | ||
| Synonyms: | US8952169, 106 | US9771376, Example 106 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H18ClF4NO4S | ||
| Mol. Mass. | 431.83 | ||
| SMILES | CS(=O)(=O)NC(=O)c1cc(Cl)c(OC[C@H]2CC[C@@H](CC2)C(F)(F)F)cc1F |r,wU:14.13,wD:17.20,(8.67,3.36,;7.34,2.59,;6.57,3.93,;8.11,1.26,;6,1.82,;4.67,2.59,;4.67,4.13,;3.33,1.82,;3.33,.28,;2,-.49,;2,-2.03,;.67,.28,;-.67,-.49,;-2,.28,;-3.33,-.49,;-3.33,-2.03,;-4.67,-2.8,;-6,-2.03,;-6,-.49,;-4.67,.28,;-7.34,-2.8,;-8.67,-3.57,;-8.11,-1.46,;-6.57,-4.13,;.67,1.82,;2,2.59,;2,4.13,)| | ||
| Structure | 
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