| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] |
|---|
| Ligand | BDBM343689 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Kinase Assay |
|---|
| IC50 | 25.0±n/a nM |
|---|
| Citation |  Eis, K; Puehler, F; Zorn, L; Schulze, V; Sülzle, D; Lienau, P; Hägebarth, A; Petersen, K; Bömer, U Amino-substituted imidazopyridazines US Patent US9777004 Publication Date 10/3/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] |
|---|
| Name: | Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] |
|---|
| Synonyms: | Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] | Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) [T344D] | MAP kinase signal-integrating kinase 1 (MNK1) (T344D) | MAP kinase-interacting serine/threonine-protein kinase 1 (MKNK1) | MAP kinase-interacting serine/threonine-protein kinase 1 (MKNK1) (T344D) | MAP kinase-interacting serine/threonine-protein kinase 1 (MKNK1)(T344D) | MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) [T344D] | MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) | MKNK1 | MKNK1 (aa 1-424) T344D | MKNK1_HUMAN | MNK1 | MNK1a |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 47416.00 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9BUB5-2 with T344D |
|---|
| Residue: | 424 |
|---|
| Sequence: | MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY
AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF
YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKGIAHRDLKPENILCES
PEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKR
CDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWA
HISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPDPQVLQRNSSTMDLTLF
AAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSP
PTAL
|
|
|
|---|
| BDBM343689 |
|---|
| n/a |
|---|
| Name | BDBM343689 |
|---|
| Synonyms: | 3-(1-Benzofuran-2-yl)-6-(piperidin-3-yloxy)imidazo[1,2-b]pyridazine | US9777004, 22 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H18N4O2 |
|---|
| Mol. Mass. | 334.3718 |
|---|
| SMILES | C1CNCC(C1)Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1 |w:6.6| |
|---|
| Structure | 
|
|---|
Search and Browse
