| Reaction Details |
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 | Report a problem with these data |
| Target | MAP kinase-activated protein kinase 2 |
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| Ligand | BDBM348778 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Mass Spectrometry Assay |
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| IC50 | <100±n/a nM |
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| Citation |  Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C MK2 inhibitors and uses thereof US Patent US9790235 Publication Date 10/17/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| MAP kinase-activated protein kinase 2 |
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| Name: | MAP kinase-activated protein kinase 2 |
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| Synonyms: | MAP kinase-activated protein kinase 2 (MAPKAPK2) | MAP kinase-activated protein kinase 2 (MK2) | MAP kinase-activated protein kinase 2 (p38/MK2) | MAPK-Activated Protein Kinase 2 (MK2) | MAPK-activated protein kinase 2 | MAPK2_HUMAN | MAPKAP kinase 2 | MAPKAPK-2 | MAPKAPK2 | MK2 |
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| Type: | Serine/threonine-protein kinase |
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| Mol. Mass.: | 45579.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49137 |
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| Residue: | 400 |
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| Sequence: | MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAII
DDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRI
VDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSI
NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY
DKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKM
LIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSAL
ATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH
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| BDBM348778 |
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| n/a |
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| Name | BDBM348778 |
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| Synonyms: | US9790235, Number I-29 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H17FN6O2S |
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| Mol. Mass. | 436.462 |
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| SMILES | C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)ncc5C(N)=O)ccc4c23)C(=O)N1 |r| |
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| Structure | 
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