Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | ||
| Ligand | BDBM354685 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | HTRF assay | ||
| IC50 | <1±n/a nM | ||
| Citation |  Armani, E; Amari, G; Blackaby, W; Van De Poel, H; Baker-Glenn, C; Trivedi, N Aminoester derivatives US Patent US9809582 Publication Date 11/7/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | |||
| Name: | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | ||
| Synonyms: | 3',5'-cyclic phosphodiesterase | DPDE4 | Isoform PDE4B1 | PDE32 | PDE4B | PDE4B1 | PDE4B_HUMAN | Phosphodiesterase 4B | Phosphodiesterase 4B (PDE4B) | Phosphodiesterase 4B (PDE4B1) | Phosphodiesterase Type 4 (PDE4B) | ||
| Type: | Protein | ||
| Mol. Mass.: | 83318.87 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q07343 | ||
| Residue: | 736 | ||
| Sequence: |
| ||
| BDBM354685 | |||
| n/a | |||
| Name | BDBM354685 | ||
| Synonyms: | US9809582, Example 30 | US9809582, Example 31 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C38H41Cl2N3O7S | ||
| Mol. Mass. | 754.719 | ||
| SMILES | COc1ccc(cc1OC)[C@H](Cc1c(Cl)c[n+]([O-])cc1Cl)OC(=O)c1ccc(CNCC(C)(C(=O)O[C@H]2CN3CCC2CC3)c2ccccc2)s1 |r,wU:10.22,wD:36.37,(-6.42,-8.8,;-5.08,-9.57,;-3.75,-8.8,;-2.41,-9.57,;-1.08,-8.8,;-1.08,-7.26,;-2.41,-6.49,;-3.75,-7.26,;-5.08,-6.49,;-6.42,-7.26,;.25,-6.49,;1.59,-7.26,;2.92,-6.49,;2.92,-4.95,;1.59,-4.18,;4.25,-4.18,;5.59,-4.95,;6.92,-4.18,;5.59,-6.49,;4.25,-7.26,;4.25,-8.8,;.25,-4.95,;-1.08,-4.18,;-2.41,-4.95,;-1.08,-2.64,;-2.33,-1.74,;-1.85,-.27,;-.31,-.27,;.46,1.06,;-.31,2.4,;.46,3.73,;.06,5.22,;-.34,6.7,;1.15,6.31,;.75,7.79,;2.64,5.91,;3.73,7,;5.21,6.6,;6.3,7.69,;5.9,9.17,;4.42,9.57,;3.33,8.48,;4.42,7.39,;5.21,8.77,;-1.43,5.61,;-2.52,4.53,;-4,4.92,;-4.4,6.41,;-3.31,7.5,;-1.83,7.1,;.16,-1.74,)| | ||
| Structure | 
| ||