| Reaction Details |
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 | Report a problem with these data |
| Target | Carnitine monooxygenase oxygenase/reductase subunit |
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| Ligand | BDBM356498 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | BCA Protein Assay |
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| IC50 | 170000±n/a nM |
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| Citation |  Garcia-Garcia, JC; Hazen, SL; Wos, JA Compounds and methods for inhibiting production of trimethylamine US Patent US10213407 Publication Date 2/26/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Carnitine monooxygenase oxygenase/reductase subunit |
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| Name: | Carnitine monooxygenase oxygenase/reductase subunit |
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| Synonyms: | BL21*DE3::pET30a-Ec yeaWX |
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| Type: | Enzyme |
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| Mol. Mass.: | n/a |
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| Description: | n/a |
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| Components: | This complex has 2 components. |
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| Component 1 |
| Name: | Carnitine monooxygenase oxygenase subunit |
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| Synonyms: | CNTA_ECOLI | Carnitine monooxygenase alpha subunit | yeaW |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42552.77 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | n/a |
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| Residue: | 374 |
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| Sequence: | MSNLSPDFVLPENFCANPQEAWTIPARFYTDQNAFEHEKENVFAKSWICVAHSSELANAN
DYVTREIIGESIVLVRGRDKVLRAFYNVCPHRGHQLLSGEGKAKNVITCPYHAWAFKLDG
NLAHARNCENVANFDSDKAQLVPVRLEEYAGFVFINMDPNATSVEDQLPGLGAKVLEACP
EVHDLKLAARFTTRTPANWKNIVDNYLECYHCGPAHPGFSDSVQVDRYWHTMHGNWTLQY
GFAKPSEQSFKFEEGTDAAFHGFWLWPCTMLNVTPIKGMMTVIYEFPVDSETTLQNYDIY
FTNEELTDEQKSLIEWYRDVFRPEDLRLVESVQKGLKSRGYRGQGRIMADSSGSGISEHG
IAHFHNLLAQVFKD
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| Component 2 |
| Name: | Carnitine monooxygenase reductase subunit |
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| Synonyms: | CNTB_ECOLI | Carnitine monooxygenase beta subunit | yeaX |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 35651.77 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | n/a |
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| Residue: | 321 |
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| Sequence: | MSDYQMFEVQVSQVEPLTEQVKRFTLVATDGKPLPAFTGGSHVIVQMSDGDNQYSNAYSL
LSSPHDTSCYQIAVRLEENSRGGSRFLHQQVKVGDRLTISTPNNLFALIPSARKHLFIAG
GIGITPFLSHMAELQHSDVDWQLHYCSRNPESCAFRDELVQHPQAEKVHLHHSSTGTRLE
LARLLADIEPGTHVYTCGPEALIEAVRSEAARLDIAADTLHFEQFAIEDKTGDAFTLVLA
RSGKEFVVPEEMTILQVIENNKAAKVECLCREGVCGTCETAILEGEADHRDQYFSDEERA
SQQSMLICCSRAKGKRLVLDL
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| BDBM356498 |
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| n/a |
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| Name | BDBM356498 |
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| Synonyms: | US10213407, ID 7 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H20BrF3N2O3S2 |
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| Mol. Mass. | 429.317 |
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| SMILES | [O-]S(=O)(=O)C(F)(F)F.CC[N+](CC)(CCBr)CCCN=C=S |
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| Structure | 
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