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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Amine oxidase [flavin-containing] A | ||
| Ligand | BDBM254560 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Biological Assays-Inhibition of LSD1 | ||
| IC50 | >100000±n/a nM | ||
| Citation |  Ortega Muñoz, A; Fyfe, MC; Martinell Pedemonte, M; Estiarte Martinez, M; Valls Vidal, N; Kurz, G; Castro Palomino Laria, JC (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors US Patent US10214477 Publication Date 2/26/2019 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Amine oxidase [flavin-containing] A | |||
| Name: | Amine oxidase [flavin-containing] A | ||
| Synonyms: | AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA) | ||
| Type: | Protein | ||
| Mol. Mass.: | 59689.53 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P21397 | ||
| Residue: | 527 | ||
| Sequence: |
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| BDBM254560 | |||
| n/a | |||
| Name | BDBM254560 | ||
| Synonyms: | US10214477, Example 19 | US9469597, 19 | US9670136, 19 N1-((trans)-2-phenylcyclopropyl)cyclobutane-1,3-diamine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C13H18N2 | ||
| Mol. Mass. | 202.2954 | ||
| SMILES | NC1CC(C1)N[C@H]1C[C@@H]1c1ccccc1 |r,wU:8.10,wD:6.6,(5.71,2.47,;4.38,1.7,;3.98,.21,;2.49,.61,;2.89,2.1,;1.16,-.16,;-.17,.61,;-.94,1.94,;-1.71,.61,;-3.05,-.16,;-3.05,-1.7,;-4.38,-2.47,;-5.71,-1.7,;-5.71,-.16,;-4.38,.61,)| | ||
| Structure | 
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