Reaction Details | |||
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Target | Amine oxidase [flavin-containing] B | ||
Ligand | BDBM254572 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Biological Assays-Inhibition of LSD1 | ||
IC50 | >100000±n/a nM | ||
Citation | Ortega Muñoz, A; Fyfe, MC; Martinell Pedemonte, M; Estiarte Martinez, M; Valls Vidal, N; Kurz, G; Castro Palomino Laria, JC (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors US Patent US10214477 Publication Date 2/26/2019 | ||
More Info.: | Get all data from this article, Assay Method | ||
Amine oxidase [flavin-containing] B | |||
Name: | Amine oxidase [flavin-containing] B | ||
Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) | ||
Type: | Protein | ||
Mol. Mass.: | 58768.76 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P27338 | ||
Residue: | 520 | ||
Sequence: |
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BDBM254572 | |||
n/a | |||
Name | BDBM254572 | ||
Synonyms: | US10214477, Example 31 | US9469597, 31 | US9670136, 31 N1-(2-(2-fluorophenyl)cyclopropyl)cyclohexane-1,4-diamine | ||
Type | Small organic molecule | ||
Emp. Form. | C15H21FN2 | ||
Mol. Mass. | 248.339 | ||
SMILES | NC1CCC(CC1)NC1CC1c1ccccc1F |(6.1,2.69,;4.77,1.92,;4.77,.38,;3.44,-.39,;2.1,.38,;2.1,1.92,;3.44,2.69,;.77,-.38,;-.56,.38,;-1.33,1.72,;-2.1,.38,;-3.44,-.38,;-4.77,.38,;-6.1,-.38,;-6.1,-1.93,;-4.77,-2.69,;-3.44,-1.93,;-2.1,-2.69,)| | ||
Structure |