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TargetKallikrein 1
LigandBDBM357210
Substrate/Competitorn/a
Meas. Tech.Kallikrein Assay
Ki 0.160±n/a nM
Citation Xu JAli AZhou WGao YEdmondson SDMertz ENeelamkavil SFLiu WSun WShen DHarper BZhu CBara TLim YYang M Factor XIA inhibitors US Patent  US10214512 Publication Date 2/26/2019
More Info.:Get all data from this article,  Assay Method
 
Kallikrein 1
Name:Kallikrein 1
Synonyms:Kallikrein 1 | Kallikrein-1 | Kidney/pancreas/salivary gland kallikrein | Tissue kallikrein
Type:Enzyme
Mol. Mass.:28874.69
Organism:Homo sapiens (Human)
Description:P06870
Residue:262
Sequence:
MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV
LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD
LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL
PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK
PSVAVRVLSYVKWIEDTIAENS
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  Blast E-value cutoff:
BDBM357210
n/a
NameBDBM357210
Synonyms:US10214512, Example 151-a
TypeSmall organic molecule
Emp. Form.C30H28ClF2N5O4
Mol. Mass.596.024
SMILESCOC(=O)Nc1ccc2-c3nc([nH]c3C)[C@H](C[C@H](C)CCC(=O)Nc2c1)c1ccc(c[n+]1[O-])-c1c(F)ccc(Cl)c1F |r|
Structure
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