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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Serine/threonine-protein kinase TBK1 | ||
| Ligand | BDBM357877 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Kinase Assays | ||
| IC50 | 190±n/a nM | ||
| Citation |  Showalter, HD; Saltiel, AR; Tesmer, JJ; Gan, X Amlexanox analogs US Patent US10214536 Publication Date 2/26/2019 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Serine/threonine-protein kinase TBK1 | |||
| Name: | Serine/threonine-protein kinase TBK1 | ||
| Synonyms: | NAK | NF-kappa-B-activating kinase | Protein cereblon/Serine/threonine-protein kinase TBK1 | T2K | TANK-binding kinase 1 (TBK-1) | TANK-binding kinase 1 (TBK1) | TBK1 | TBK1_HUMAN | ||
| Type: | protein | ||
| Mol. Mass.: | 83645.20 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q9UHD2 | ||
| Residue: | 729 | ||
| Sequence: |
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| BDBM357877 | |||
| n/a | |||
| Name | BDBM357877 | ||
| Synonyms: | US10214536, Compound 53 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H18N2O5 | ||
| Mol. Mass. | 354.3566 | ||
| SMILES | Nc1nc2oc3ccc(cc3c(=O)c2cc1C(O)=O)C1CCC(O)CC1 |(6.67,2.69,;5.33,1.93,;4,2.69,;2.67,1.93,;1.33,2.69,;,1.93,;-1.33,2.69,;-2.67,1.93,;-2.67,.38,;-1.33,-.38,;,.38,;1.33,-.38,;1.33,-1.93,;2.67,.38,;4,-.38,;5.33,.38,;6.67,-.38,;8,.38,;6.67,-1.93,;-4,-.38,;-5.33,.38,;-6.67,-.38,;-6.67,-1.93,;-8,-2.69,;-5.33,-2.69,;-4,-1.93,)| | ||
| Structure | 
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