Found 420 hits with Last Name = 'gan' and Initial = 'x' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50432208
(CHEMBL2347110)Show SMILES COc1cc2N(O)C(=O)[C@@H](N)Cc2cc1Cc1ccccc1 |r| Show InChI InChI=1S/C17H18N2O3/c1-22-16-10-15-12(9-14(18)17(20)19(15)21)8-13(16)7-11-5-3-2-4-6-11/h2-6,8,10,14,21H,7,9,18H2,1H3/t14-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysis |
Bioorg Med Chem Lett 23: 1961-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.039 BindingDB Entry DOI: 10.7270/Q2N87C48 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50426340
(CHEMBL2321943)Show SMILES COc1cc2N(O)C(=O)[C@@H](N)Cc2cc1Oc1ccccc1 |r| Show InChI InChI=1S/C16H16N2O4/c1-21-14-9-13-10(7-12(17)16(19)18(13)20)8-15(14)22-11-5-3-2-4-6-11/h2-6,8-9,12,20H,7,17H2,1H3/t12-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Irreversible inhibition of human KAT2 using L-kynurenine as substrate measured every 5 mins over 16 hrs by SpectraMax plate reader analysis |
ACS Med Chem Lett 4: 37-40 (2013)
Article DOI: 10.1021/ml300237v BindingDB Entry DOI: 10.7270/Q2KH0PNV |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM107730
(CHEMBL2347108 | US8933095, 14)Show InChI InChI=1S/C12H12N4O2/c13-10-6-8-7-15(9-4-2-1-3-5-9)14-11(8)16(18)12(10)17/h1-5,7,10,18H,6,13H2/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysis |
Bioorg Med Chem Lett 23: 1961-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.039 BindingDB Entry DOI: 10.7270/Q2N87C48 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50124566
((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)Show InChI InChI=1S/C19H23NO3/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18/h3-11,18-20H,2,12-14H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50136680
(CHEMBL424660 | N-methyl-3-(1-naphthyloxy)-3-(2-thi...)Show InChI InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM87043
((R)-2-((R)-(4-fluoro-2-methoxyphenoxy)(phenyl)meth...)Show InChI InChI=1S/C18H20FNO3/c1-21-16-11-14(19)7-8-15(16)23-18(13-5-3-2-4-6-13)17-12-20-9-10-22-17/h2-8,11,17-18,20H,9-10,12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50426341
(CHEMBL2321944)Show InChI InChI=1S/C15H14N2O3/c16-13-9-10-8-12(20-11-4-2-1-3-5-11)6-7-14(10)17(19)15(13)18/h1-8,13,19H,9,16H2/t13-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Irreversible inhibition of human KAT2 using L-kynurenine as substrate measured every 5 mins over 16 hrs by SpectraMax plate reader analysis |
ACS Med Chem Lett 4: 37-40 (2013)
Article DOI: 10.1021/ml300237v BindingDB Entry DOI: 10.7270/Q2KH0PNV |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50386310
(CHEMBL2049092)Show InChI InChI=1S/C10H12N2O3/c1-15-7-3-2-6-4-8(11)10(13)12(14)9(6)5-7/h2-3,5,8,14H,4,11H2,1H3/t8-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Irreversible inhibition of human KAT2 using L-kynurenine as substrate measured every 5 mins over 16 hrs by SpectraMax plate reader analysis |
ACS Med Chem Lett 4: 37-40 (2013)
Article DOI: 10.1021/ml300237v BindingDB Entry DOI: 10.7270/Q2KH0PNV |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM87036
((R)-2-((R)-(4-chloro-2-methoxyphenoxy)(phenyl)meth...)Show InChI InChI=1S/C18H20ClNO3/c1-21-16-11-14(19)7-8-15(16)23-18(13-5-3-2-4-6-13)17-12-20-9-10-22-17/h2-8,11,17-18,20H,9-10,12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM87037
((S)-2-((S)-(4-chloro-2-methoxyphenoxy)(3-fluorophe...)Show InChI InChI=1S/C18H19ClFNO3/c1-22-16-10-13(19)5-6-15(16)24-18(17-11-21-7-8-23-17)12-3-2-4-14(20)9-12/h2-6,9-10,17-18,21H,7-8,11H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM87027
((R)-2-((R)-(2,3-difluorophenoxy)(phenyl)methyl)mor...)Show InChI InChI=1S/C17H17F2NO2/c18-13-7-4-8-14(16(13)19)22-17(12-5-2-1-3-6-12)15-11-20-9-10-21-15/h1-8,15,17,20H,9-11H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM87024
((R)-2-((R)-(4-fluoro-2-methylphenoxy)(phenyl)methy...)Show InChI InChI=1S/C18H20FNO2/c1-13-11-15(19)7-8-16(13)22-18(14-5-3-2-4-6-14)17-12-20-9-10-21-17/h2-8,11,17-18,20H,9-10,12H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM87043
((R)-2-((R)-(4-fluoro-2-methoxyphenoxy)(phenyl)meth...)Show InChI InChI=1S/C18H20FNO3/c1-21-16-11-14(19)7-8-15(16)23-18(13-5-3-2-4-6-13)17-12-20-9-10-22-17/h2-8,11,17-18,20H,9-10,12H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM87032
((R)-2-((R)-(2-chloro-4-fluorophenoxy)(phenyl)methy...)Show InChI InChI=1S/C17H17ClFNO2/c18-14-10-13(19)6-7-15(14)22-17(12-4-2-1-3-5-12)16-11-20-8-9-21-16/h1-7,10,16-17,20H,8-9,11H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM87025
((R)-2-((R)-(2,3-dihydrobenzofuran-7-yloxy)(phenyl)...)Show InChI InChI=1S/C19H21NO3/c1-2-5-14(6-3-1)19(17-13-20-10-12-21-17)23-16-8-4-7-15-9-11-22-18(15)16/h1-8,17,19-20H,9-13H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM87027
((R)-2-((R)-(2,3-difluorophenoxy)(phenyl)methyl)mor...)Show InChI InChI=1S/C17H17F2NO2/c18-13-7-4-8-14(16(13)19)22-17(12-5-2-1-3-6-12)15-11-20-9-10-21-15/h1-8,15,17,20H,9-11H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM87036
((R)-2-((R)-(4-chloro-2-methoxyphenoxy)(phenyl)meth...)Show InChI InChI=1S/C18H20ClNO3/c1-21-16-11-14(19)7-8-15(16)23-18(13-5-3-2-4-6-13)17-12-20-9-10-22-17/h2-8,11,17-18,20H,9-10,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM87028
((S)-2-((S)-(4-bromo-2-methoxyphenoxy)(phenyl)methy...)Show InChI InChI=1S/C18H20BrNO3/c1-21-16-11-14(19)7-8-15(16)23-18(13-5-3-2-4-6-13)17-12-20-9-10-22-17/h2-8,11,17-18,20H,9-10,12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM107747
(CHEMBL2347115 | US8933095, 4)Show InChI InChI=1S/C13H14N4O2/c14-10-6-11-12(17(19)13(10)18)7-15-16(11)8-9-4-2-1-3-5-9/h1-5,7,10,19H,6,8,14H2/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysis |
Bioorg Med Chem Lett 23: 1961-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.039 BindingDB Entry DOI: 10.7270/Q2N87C48 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM87032
((R)-2-((R)-(2-chloro-4-fluorophenoxy)(phenyl)methy...)Show InChI InChI=1S/C17H17ClFNO2/c18-14-10-13(19)6-7-15(14)22-17(12-4-2-1-3-5-12)16-11-20-8-9-21-16/h1-7,10,16-17,20H,8-9,11H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM87025
((R)-2-((R)-(2,3-dihydrobenzofuran-7-yloxy)(phenyl)...)Show InChI InChI=1S/C19H21NO3/c1-2-5-14(6-3-1)19(17-13-20-10-12-21-17)23-16-8-4-7-15-9-11-22-18(15)16/h1-8,17,19-20H,9-13H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50386292
(CHEMBL2047851)Show InChI InChI=1S/C9H10N2O2/c10-7-5-6-3-1-2-4-8(6)11(13)9(7)12/h1-4,7,13H,5,10H2/t7-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysis |
Bioorg Med Chem Lett 23: 1961-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.039 BindingDB Entry DOI: 10.7270/Q2N87C48 |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50386292
(CHEMBL2047851)Show InChI InChI=1S/C9H10N2O2/c10-7-5-6-3-1-2-4-8(6)11(13)9(7)12/h1-4,7,13H,5,10H2/t7-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Irreversible inhibition of human KAT2 using L-kynurenine as substrate measured every 5 mins over 16 hrs by SpectraMax plate reader analysis |
ACS Med Chem Lett 4: 37-40 (2013)
Article DOI: 10.1021/ml300237v BindingDB Entry DOI: 10.7270/Q2KH0PNV |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM87030
(CAS_44449911 | NSC_44449911 | rac-syn-2-((4-chloro...)Show InChI InChI=1S/C19H22ClNO3/c1-2-22-17-12-15(20)8-9-16(17)24-19(14-6-4-3-5-7-14)18-13-21-10-11-23-18/h3-9,12,18-19,21H,2,10-11,13H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM87038
((S)-2-((S)-(4-chloro-2-methoxyphenoxy)(m-tolyl)met...)Show InChI InChI=1S/C19H22ClNO3/c1-13-4-3-5-14(10-13)19(18-12-21-8-9-23-18)24-16-7-6-15(20)11-17(16)22-2/h3-7,10-11,18-19,21H,8-9,12H2,1-2H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM87029
((S)-2-((S)-(2,3-dichlorophenoxy)(phenyl)methyl)mor...)Show InChI InChI=1S/C17H17Cl2NO2/c18-13-7-4-8-14(16(13)19)22-17(12-5-2-1-3-6-12)15-11-20-9-10-21-15/h1-8,15,17,20H,9-11H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM87024
((R)-2-((R)-(4-fluoro-2-methylphenoxy)(phenyl)methy...)Show InChI InChI=1S/C18H20FNO2/c1-13-11-15(19)7-8-16(13)22-18(14-5-3-2-4-6-14)17-12-20-9-10-21-17/h2-8,11,17-18,20H,9-10,12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM87025
((R)-2-((R)-(2,3-dihydrobenzofuran-7-yloxy)(phenyl)...)Show InChI InChI=1S/C19H21NO3/c1-2-5-14(6-3-1)19(17-13-20-10-12-21-17)23-16-8-4-7-15-9-11-22-18(15)16/h1-8,17,19-20H,9-13H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM87032
((R)-2-((R)-(2-chloro-4-fluorophenoxy)(phenyl)methy...)Show InChI InChI=1S/C17H17ClFNO2/c18-14-10-13(19)6-7-15(14)22-17(12-4-2-1-3-5-12)16-11-20-8-9-21-16/h1-7,10,16-17,20H,8-9,11H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM107738
(CHEMBL2347113 | US8933095, 22)Show SMILES COc1cccc(Cc2nn(C)c3N(O)C(=O)[C@@H](N)Cc23)c1 |r| Show InChI InChI=1S/C15H18N4O3/c1-18-14-11(8-12(16)15(20)19(14)21)13(17-18)7-9-4-3-5-10(6-9)22-2/h3-6,12,21H,7-8,16H2,1-2H3/t12-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysis |
Bioorg Med Chem Lett 23: 1961-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.039 BindingDB Entry DOI: 10.7270/Q2N87C48 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM87023
((S)-2-((S)-(4-chloro-2-methoxyphenoxy)(2-fluorophe...)Show InChI InChI=1S/C18H19ClFNO3/c1-22-16-10-12(19)6-7-15(16)24-18(17-11-21-8-9-23-17)13-4-2-3-5-14(13)20/h2-7,10,17-18,21H,8-9,11H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM87043
((R)-2-((R)-(4-fluoro-2-methoxyphenoxy)(phenyl)meth...)Show InChI InChI=1S/C18H20FNO3/c1-21-16-11-14(19)7-8-15(16)23-18(13-5-3-2-4-6-13)17-12-20-9-10-22-17/h2-8,11,17-18,20H,9-10,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM107746
(CHEMBL2347107 | US8933095, 1)Show InChI InChI=1S/C13H14N4O2/c14-11-6-10-8-16(7-9-4-2-1-3-5-9)15-12(10)17(19)13(11)18/h1-5,8,11,19H,6-7,14H2/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysis |
Bioorg Med Chem Lett 23: 1961-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.039 BindingDB Entry DOI: 10.7270/Q2N87C48 |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM87036
((R)-2-((R)-(4-chloro-2-methoxyphenoxy)(phenyl)meth...)Show InChI InChI=1S/C18H20ClNO3/c1-21-16-11-14(19)7-8-15(16)23-18(13-5-3-2-4-6-13)17-12-20-9-10-22-17/h2-8,11,17-18,20H,9-10,12H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM87036
((R)-2-((R)-(4-chloro-2-methoxyphenoxy)(phenyl)meth...)Show InChI InChI=1S/C18H20ClNO3/c1-21-16-11-14(19)7-8-15(16)23-18(13-5-3-2-4-6-13)17-12-20-9-10-22-17/h2-8,11,17-18,20H,9-10,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM87046
((S)-2-((S)-(2-chloro-4-methoxyphenoxy)(phenyl)meth...)Show InChI InChI=1S/C18H20ClNO3/c1-21-14-7-8-16(15(19)11-14)23-18(13-5-3-2-4-6-13)17-12-20-9-10-22-17/h2-8,11,17-18,20H,9-10,12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM87031
((S)-2-((S)-(4-chloro-2-methoxyphenoxy)(4-fluorophe...)Show InChI InChI=1S/C18H19ClFNO3/c1-22-16-10-13(19)4-7-15(16)24-18(17-11-21-8-9-23-17)12-2-5-14(20)6-3-12/h2-7,10,17-18,21H,8-9,11H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM87028
((S)-2-((S)-(4-bromo-2-methoxyphenoxy)(phenyl)methy...)Show InChI InChI=1S/C18H20BrNO3/c1-21-16-11-14(19)7-8-15(16)23-18(13-5-3-2-4-6-13)17-12-20-9-10-22-17/h2-8,11,17-18,20H,9-10,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM107720
(CHEMBL2347112 | US8598200, 2)Show SMILES Cn1nc(Cc2ccccc2)c2C[C@H](N)C(=O)N(O)c12 |r| Show InChI InChI=1S/C14H16N4O2/c1-17-13-10(8-11(15)14(19)18(13)20)12(16-17)7-9-5-3-2-4-6-9/h2-6,11,20H,7-8,15H2,1H3/t11-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysis |
Bioorg Med Chem Lett 23: 1961-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.039 BindingDB Entry DOI: 10.7270/Q2N87C48 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM87024
((R)-2-((R)-(4-fluoro-2-methylphenoxy)(phenyl)methy...)Show InChI InChI=1S/C18H20FNO2/c1-13-11-15(19)7-8-16(13)22-18(14-5-3-2-4-6-14)17-12-20-9-10-21-17/h2-8,11,17-18,20H,9-10,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM87036
((R)-2-((R)-(4-chloro-2-methoxyphenoxy)(phenyl)meth...)Show InChI InChI=1S/C18H20ClNO3/c1-21-16-11-14(19)7-8-15(16)23-18(13-5-3-2-4-6-13)17-12-20-9-10-22-17/h2-8,11,17-18,20H,9-10,12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM50432200
(CHEMBL2347109 | US8933095, 16)Show InChI InChI=1S/C12H12N4O2/c13-9-6-10-11(16(18)12(9)17)7-15(14-10)8-4-2-1-3-5-8/h1-5,7,9,18H,6,13H2/t9-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysis |
Bioorg Med Chem Lett 23: 1961-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.039 BindingDB Entry DOI: 10.7270/Q2N87C48 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM87040
((S)-2-((S)-(2-methoxy-4-(trifluoromethyl)phenoxy)(...)Show InChI InChI=1S/C19H20F3NO3/c1-24-16-11-14(19(20,21)22)7-8-15(16)26-18(13-5-3-2-4-6-13)17-12-23-9-10-25-17/h2-8,11,17-18,23H,9-10,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50136680
(CHEMBL424660 | N-methyl-3-(1-naphthyloxy)-3-(2-thi...)Show InChI InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
(Homo sapiens (Human)) | BDBM107722
(CHEMBL2347114 | US8933095, 5)Show SMILES N[C@H]1Cc2c(N(O)C1=O)c(nn2Cc1ccccc1)C(F)(F)F |r| Show InChI InChI=1S/C14H13F3N4O2/c15-14(16,17)12-11-10(6-9(18)13(22)21(11)23)20(19-12)7-8-4-2-1-3-5-8/h1-5,9,23H,6-7,18H2/t9-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysis |
Bioorg Med Chem Lett 23: 1961-6 (2013)
Article DOI: 10.1016/j.bmcl.2013.02.039 BindingDB Entry DOI: 10.7270/Q2N87C48 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM87037
((S)-2-((S)-(4-chloro-2-methoxyphenoxy)(3-fluorophe...)Show InChI InChI=1S/C18H19ClFNO3/c1-22-16-10-13(19)5-6-15(16)24-18(17-11-21-7-8-23-17)12-3-2-4-14(20)9-12/h2-6,9-10,17-18,21H,7-8,11H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM87036
((R)-2-((R)-(4-chloro-2-methoxyphenoxy)(phenyl)meth...)Show InChI InChI=1S/C18H20ClNO3/c1-21-16-11-14(19)7-8-15(16)23-18(13-5-3-2-4-6-13)17-12-20-9-10-22-17/h2-8,11,17-18,20H,9-10,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM87030
(CAS_44449911 | NSC_44449911 | rac-syn-2-((4-chloro...)Show InChI InChI=1S/C19H22ClNO3/c1-2-22-17-12-15(20)8-9-16(17)24-19(14-6-4-3-5-7-14)18-13-21-10-11-23-18/h3-9,12,18-19,21H,2,10-11,13H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM87031
((S)-2-((S)-(4-chloro-2-methoxyphenoxy)(4-fluorophe...)Show InChI InChI=1S/C18H19ClFNO3/c1-22-16-10-13(19)4-7-15(16)24-18(17-11-21-8-9-23-17)12-2-5-14(20)6-3-12/h2-7,10,17-18,21H,8-9,11H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM87038
((S)-2-((S)-(4-chloro-2-methoxyphenoxy)(m-tolyl)met...)Show InChI InChI=1S/C19H22ClNO3/c1-13-4-3-5-14(10-13)19(18-12-21-8-9-23-18)24-16-7-6-15(20)11-17(16)22-2/h3-7,10-11,18-19,21H,8-9,12H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 2562-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.050 BindingDB Entry DOI: 10.7270/Q2Z036RS |
More data for this Ligand-Target Pair | |