| Reaction Details |
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 | Report a problem with these data |
| Target | Papain |
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| Ligand | BDBM20110 |
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| Substrate/Competitor | BDBM20081 |
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| Meas. Tech. | Papain Inhibition Assay |
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| Ki | 7600±n/a nM |
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| Citation |  Löser, R; Schilling, K; Dimmig, E; Gütschow, M Interaction of papain-like cysteine proteases with dipeptide-derived nitriles. J Med Chem48:7688-707 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Papain |
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| Name: | Papain |
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| Synonyms: | Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I |
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| Type: | Enzyme |
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| Mol. Mass.: | 38923.01 |
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| Organism: | Carica papaya |
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| Description: | Papain was purchased from Sigma, Germany. |
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| Residue: | 345 |
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| Sequence: | MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYK
NIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTE
LSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNE
YSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKT
DGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYG
PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
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| BDBM20110 |
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| BDBM20081 |
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| Name | BDBM20110 |
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| Synonyms: | dipeptide-derived nitrile, 31 | tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-(1H-indol-3-yl)ethyl]carbamate |
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| Type | Small organic molecule |
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| Emp. Form. | C18H22N4O3 |
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| Mol. Mass. | 342.3923 |
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| SMILES | CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC#N |r| |
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| Structure | 
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