| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Papain |
|---|
| Ligand | BDBM20127 |
|---|
| Substrate/Competitor | BDBM20081 |
|---|
| Meas. Tech. | Papain Inhibition Assay |
|---|
| Ki | 497000±n/a nM |
|---|
| Citation |  Löser, R; Schilling, K; Dimmig, E; Gütschow, M Interaction of papain-like cysteine proteases with dipeptide-derived nitriles. J Med Chem48:7688-707 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Papain |
|---|
| Name: | Papain |
|---|
| Synonyms: | Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 38923.01 |
|---|
| Organism: | Carica papaya |
|---|
| Description: | Papain was purchased from Sigma, Germany. |
|---|
| Residue: | 345 |
|---|
| Sequence: | MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYK
NIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTE
LSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNE
YSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKT
DGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYG
PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
|
|
|
|---|
| BDBM20127 |
|---|
| BDBM20081 |
|---|
| Name | BDBM20127 |
|---|
| Synonyms: | phenylalanine derived allylamide, 55 | tert-butyl N-[(1S)-2-phenyl-1-(prop-2-en-1-ylcarbamoyl)ethyl]carbamate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H24N2O3 |
|---|
| Mol. Mass. | 304.3841 |
|---|
| SMILES | CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC=C |r| |
|---|
| Structure | 
|
|---|
Search and Browse
