| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin S |
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| Ligand | BDBM20126 |
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| Substrate/Competitor | BDBM20129 |
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| Meas. Tech. | Papain Inhibition Assay |
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| Ki | >100000±n/a nM |
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| Citation |  Löser, R; Schilling, K; Dimmig, E; Gütschow, M Interaction of papain-like cysteine proteases with dipeptide-derived nitriles. J Med Chem48:7688-707 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Cathepsin S |
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| Name: | Cathepsin S |
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| Synonyms: | CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein |
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| Type: | Protein |
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| Mol. Mass.: | 37507.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25774 |
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| Residue: | 331 |
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| Sequence: | MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM
LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD
WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC
NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE
AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW
GHNFGEEGYIRMARNKGNHCGIASFPSYPEI
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| BDBM20126 |
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| BDBM20129 |
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| Name | BDBM20126 |
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| Synonyms: | phenylalanine derived propargyl, 54 | tert-butyl N-[(1S)-2-phenyl-1-(prop-2-yn-1-ylcarbamoyl)ethyl]carbamate |
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| Type | Small organic molecule |
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| Emp. Form. | C17H22N2O3 |
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| Mol. Mass. | 302.3682 |
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| SMILES | CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C |r| |
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| Structure | 
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