| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM364549 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | kappa-Opioid Receptor Binding Assay |
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| Ki | 0.096±0.026 nM |
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| Citation |  Youngman, M Opioid receptor modulating oxabicyclo[2.2.2]octane morphinans US Patent US9862726 Publication Date 1/9/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM364549 |
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| n/a |
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| Name | BDBM364549 |
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| Synonyms: | (4bR,6S,8aS,9R)-6-amino-11- (cyclopropylmethyl)-5,6,7,8,9,10- hexahydro- 9,4b-(epiminoethano)-8a,6- (epoxymethano)phenanthren-3-ol | US9862726, Compound 17 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H28N2O2 |
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| Mol. Mass. | 340.4592 |
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| SMILES | NC12CC[C@@]3(OC1)[C@H]1Cc4ccc(O)cc4[C@@]3(CCN1CC1CC1)C2 |r,TLB:20:19:4:15.9.8| |
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| Structure | 
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