| Reaction Details |
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 | Report a problem with these data |
| Target | Vascular endothelial growth factor A |
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| Ligand | BDBM373050 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ELISA Assay |
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| EC50 | 14.0±n/a nM |
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| Citation |  Dixon, DD; Grina, J; Josey, JA; Rizzi, JP; Schlachter, ST; Wallace, EM; Wang, B; Wehn, P; Xu, R; Yang, H Aryl ethers and uses thereof US Patent US9908845 Publication Date 3/6/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Vascular endothelial growth factor A |
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| Name: | Vascular endothelial growth factor A |
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| Synonyms: | VEGF | VEGF-A | VEGFA | VEGFA_HUMAN | VPF | Vascular endothelial growth factor (VEGF) | Vascular endothelial growth factor A (VEGF) | Vascular endothelial growth factor A (VEGF2) | Vascular permeability factor |
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| Type: | Protein |
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| Mol. Mass.: | 27063.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P15692 |
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| Residue: | 395 |
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| Sequence: | MTDRQTDTAPSPSYHLLPGRRRTVDAAASRGQGPEPAPGGGVEGVGARGVALKLFVQLLG
CSRFGGAVVRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWT
GEAAVCADSAPAARAPQALARASGRGGRVARRGAEESGPPHSPSRRGSASRAGPGRASET
MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVD
IFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEM
SFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVPCGPCSERRKHLFVQ
DPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
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| BDBM373050 |
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| n/a |
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| Name | BDBM373050 |
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| Synonyms: | US10597366, Compound 316 | US9896418, Compound 316 | US9896418, Compound 317 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H11F4N3O3S |
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| Mol. Mass. | 425.357 |
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| SMILES | CS(=O)(=NC#N)c1ccc(Oc2cc(F)cc(c2)C#N)c2[C@@H](F)C(F)(F)[C@@H](O)c12 |r| |
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| Structure | 
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