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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Vitamin D3 receptor | ||
| Ligand | BDBM263449 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Dopamine D3 Receptor Binding Test | ||
| Ki | 0.090±n/a nM | ||
| Citation |  Li, J; Chen, X; Ma, Z; Zhang, L; Cui, N Benzoisothiazole compounds and methods of treating schizophrenia US Patent US9550741 Publication Date 1/24/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Vitamin D3 receptor | |||
| Name: | Vitamin D3 receptor | ||
| Synonyms: | 1,25-dihydroxyvitamin D3 receptor | NR1I1 | Nuclear receptor subfamily 1 group I member 1 | Retinoic acid receptor RXR-alpha/Vitamin D3 receptor | VDR | VDR_HUMAN | ||
| Type: | Protein | ||
| Mol. Mass.: | 48288.72 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P11473 | ||
| Residue: | 427 | ||
| Sequence: |
| ||
| BDBM263449 | |||
| n/a | |||
| Name | BDBM263449 | ||
| Synonyms: | US9550741, RGH-188 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H32Cl2N4O | ||
| Mol. Mass. | 427.411 | ||
| SMILES | CN(C)C(=O)NC1CCC(CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 |(,-4.62,;1.33,-5.39,;2.67,-4.62,;1.33,-6.93,;,-7.7,;2.67,-7.7,;2.67,-9.24,;4,-10.01,;4,-11.55,;2.67,-12.32,;2.67,-13.86,;4,-14.63,;4,-16.17,;5.33,-16.94,;5.33,-18.48,;4,-19.25,;2.67,-18.48,;2.67,-16.94,;4,-20.79,;2.67,-21.56,;2.67,-23.1,;4,-23.87,;5.33,-23.1,;6.67,-23.87,;5.33,-21.56,;6.67,-20.79,;1.33,-11.55,;1.33,-10.01,)| | ||
| Structure | 
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