| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Calcium-dependent protein kinase 1 |
|---|
| Ligand | BDBM50446171 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibition Assay |
|---|
| IC50 | 10.00±n/a nM |
|---|
| Citation |  Fan, E; Van Voorhis, WC; Zhang, Z; Huang, W; Ojo, KK 5-aminopyrazole-4-carboxamide inhibitors of CDPK1 from T. gondii and C. parvum US Patent US9956214 Publication Date 5/1/2018 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Calcium-dependent protein kinase 1 |
|---|
| Name: | Calcium-dependent protein kinase 1 |
|---|
| Synonyms: | Calcium-dependent protein kinase 1 (CDPK1) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 76617.33 |
|---|
| Organism: | Cryptosporidium parvum |
|---|
| Description: | Q6S4W0 |
|---|
| Residue: | 677 |
|---|
| Sequence: | MLNIEQNADECAKRVGANMVPVLHNVTEECNIKAEEKEIVPEVEEAKSESNNCLDSDDYL
EGHIYAAMCTKCAGELQQKLNPTEPYRDPKKVSGKEQISRGLIIESKSFVDANKNIKFSK
RSDKNEYAGLCSSPEVTTPNGERETSTDSNIKNTESTKVSHGIFDRTCLIQEHALVNRNI
NDFYELNLGNLGRGSYGSVVKAIDKQSGAQRAVKIILKPKLENINRLKREILIMKRLDHP
NIIKLFEVFEDTNYLYFVMEICTGGELFDRIIKRGHFSERYAAVIMRQVFSAIAYCHSNE
FMHRDLKPENLLFSDSSPNSLLKVIDWGFAAKCPKTHKFTSVVGTPYYVAPEVLYGSYSK
LCDLWSAGVILYILLCGYPPFHGKDNVEILRKVKIGQYSLEHNSWKYVSDSAKDLIKRLL
MTDPNKRISAQDALNHPWIKSQISSPNTADATYFTNDVCNSLLARFRDFQRQSKLKKLAL
TCVAYHLNDADIGALQKLFSTLDRNGDGVLTINEIRSALHKIQNVSQLGDDIDNLLMELD
TDGNGRIDYTEFIAASIDHKLYEQESLCKAAFKVFDLDMDGRISPQELSRVLNITFLQEA
FEQSTIDSLLKEVDINQDGYIDFNEFMKMMMGDKHEQKLETKVQKIEDEGSGNKKLSKGG
IISDIFGATSIFKKLNN
|
|
|
|---|
| BDBM50446171 |
|---|
| n/a |
|---|
| Name | BDBM50446171 |
|---|
| Synonyms: | CHEMBL3108999 | US9518026, Example 26 | US9956214, Compound 26 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H26N4O2 |
|---|
| Mol. Mass. | 366.4567 |
|---|
| SMILES | CCCOc1ccc2cc(ccc2c1)-c1nn(c(N)c1C(N)=O)C(C)(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
