| Reaction Details |
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 | Report a problem with these data |
| Target | Calcium-dependent protein kinase 1 |
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| Ligand | BDBM50148632 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 5.00±n/a nM |
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| Citation |  Fan, E; Van Voorhis, WC; Zhang, Z; Huang, W; Ojo, KK 5-aminopyrazole-4-carboxamide inhibitors of CDPK1 from T. gondii and C. parvum US Patent US9956214 Publication Date 5/1/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcium-dependent protein kinase 1 |
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| Name: | Calcium-dependent protein kinase 1 |
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| Synonyms: | Calcium-dependent protein kinase 1 (CDPK1) |
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| Type: | Protein |
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| Mol. Mass.: | 76617.33 |
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| Organism: | Cryptosporidium parvum |
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| Description: | Q6S4W0 |
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| Residue: | 677 |
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| Sequence: | MLNIEQNADECAKRVGANMVPVLHNVTEECNIKAEEKEIVPEVEEAKSESNNCLDSDDYL
EGHIYAAMCTKCAGELQQKLNPTEPYRDPKKVSGKEQISRGLIIESKSFVDANKNIKFSK
RSDKNEYAGLCSSPEVTTPNGERETSTDSNIKNTESTKVSHGIFDRTCLIQEHALVNRNI
NDFYELNLGNLGRGSYGSVVKAIDKQSGAQRAVKIILKPKLENINRLKREILIMKRLDHP
NIIKLFEVFEDTNYLYFVMEICTGGELFDRIIKRGHFSERYAAVIMRQVFSAIAYCHSNE
FMHRDLKPENLLFSDSSPNSLLKVIDWGFAAKCPKTHKFTSVVGTPYYVAPEVLYGSYSK
LCDLWSAGVILYILLCGYPPFHGKDNVEILRKVKIGQYSLEHNSWKYVSDSAKDLIKRLL
MTDPNKRISAQDALNHPWIKSQISSPNTADATYFTNDVCNSLLARFRDFQRQSKLKKLAL
TCVAYHLNDADIGALQKLFSTLDRNGDGVLTINEIRSALHKIQNVSQLGDDIDNLLMELD
TDGNGRIDYTEFIAASIDHKLYEQESLCKAAFKVFDLDMDGRISPQELSRVLNITFLQEA
FEQSTIDSLLKEVDINQDGYIDFNEFMKMMMGDKHEQKLETKVQKIEDEGSGNKKLSKGG
IISDIFGATSIFKKLNN
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| BDBM50148632 |
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| n/a |
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| Name | BDBM50148632 |
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| Synonyms: | CHEMBL3770409 | US9518026, Example 40 | US9956214, Compound 1572 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21N5O2 |
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| Mol. Mass. | 339.3916 |
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| SMILES | CCOc1ccc2cc(cnc2c1)-c1nn(C(C)C)c(N)c1C(N)=O |
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| Structure | 
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