| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 3 |
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| Ligand | BDBM392683 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Test for Evaluating Human MC Receptor Activation, Using Cells Expressing Human MC4, MC1, or MC3 Receptor |
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| EC50 | 2900±n/a nM |
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| Citation |  Sugane, T; Makino, T; Yamashita, D; Yonetoku, Y; Tanabe, D; Mihara, H; Asai, N; Osoda, K; Shimizu, T; Moritomo, H; Sugasawa, K; Maeno, K; Hosogai, N Piperazine derivative US Patent US10301286 Publication Date 5/28/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 3 |
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| Name: | Melanocortin receptor 3 |
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| Synonyms: | MC3-R | MC3R | MC3R_HUMAN | Melanocortin MC3 | Melanocortin receptor (M3 and M4) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36044.86 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41968 |
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| Residue: | 323 |
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| Sequence: | MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVI
LAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIF
DSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFI
VYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKG
AVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYA
FRSLELRNTFREILCGCNGMNLG
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| BDBM392683 |
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| n/a |
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| Name | BDBM392683 |
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| Synonyms: | US10301286, Example 69 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H38ClF2N3O4 |
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| Mol. Mass. | 578.09 |
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| SMILES | COc1ccc(C[C@H](N2CCN([C@@H](C)C2)C(=O)[C@@H]2CN(C[C@H]2c2ccc(Cl)cc2F)C(C)(C)C)C(O)=O)c(F)c1 |r| |
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| Structure | 
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