BindingDB PrimarySearch

Found 318 hits with Last Name = 'moritomo' and Initial = 'h'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50593531 (ASP-5878 \| ASP5878 \| Asp 5878 \| Asp-5878 \| Asp5878) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50593531 (ASP-5878 \| ASP5878 \| Asp 5878 \| Asp-5878 \| Asp5878) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 6 (Homo sapiens (Human))	BDBM50243934 (2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2,3,6-triflu...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells				Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593524 (CHEMBL5206147) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593521 (CHEMBL5182779) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593525 (CHEMBL5182060) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593522 (CHEMBL5170802) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50559408 (CHEMBL4763773) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged FGFR2 (399 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50559408 (CHEMBL4763773) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged FGFR3 (436 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593530 (CHEMBL5201061) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593526 (CHEMBL5197399) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593520 (CHEMBL5194555) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 6 (Homo sapiens (Human))	BDBM50244291 (4-[(2-Fluorobenzyl)amino]-2-[(4-morpholin-4-ylphen...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells				Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593532 (CHEMBL5193271) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50559406 (CHEMBL4746045) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged FGFR3 (436 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593523 (CHEMBL5171147) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 6 (Homo sapiens (Human))	BDBM50243884 (4-[(2,5-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells				Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50559408 (CHEMBL4763773) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged FGFR1 (398 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593533 (CHEMBL5207973) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 6 (Homo sapiens (Human))	BDBM50244292 (4-[(3-Fluorobenzyl)amino]-2-[(4-morpholin-4-ylphen...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells				Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545477 (CHEMBL4635544) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 6 (Homo sapiens (Human))	BDBM50243933 (2-[(4-Morpholin-4-ylphenyl)amino]-4-[(2,3,5-triflu...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells				Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593527 (CHEMBL5191170) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593531 (ASP-5878 \| ASP5878 \| Asp 5878 \| Asp-5878 \| Asp5878) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50545472 (CHEMBL4642080) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR1 cytoplasmic domain (398-822 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 6 (Homo sapiens (Human))	BDBM50243882 (4-[(2,3-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells				Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 6 (Homo sapiens (Human))	BDBM50243885 (4-[(2,6-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells				Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM25018 (3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...) Show SMILES Oc1cccc(c1)-c1nc(N2CCOCC2)c2sccc2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of p110alpha by SPA assay				Bioorg Med Chem Lett 17: 2438-42 (2007) Article DOI: 10.1016/j.bmcl.2007.02.032 BindingDB Entry DOI: 10.7270/Q28053F2
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593529 (CHEMBL5197909) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545471 (CHEMBL4634918) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50525939 (Balversa \| Erdafitinib \| Jnj-42756493) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal His6 tagged FGFR3 (447 to 761 residues) expressed in Sf21 cells using FLT3 peptide as substrate preincubat...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM25045 (3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of p110beta				Bioorg Med Chem Lett 17: 2438-42 (2007) Article DOI: 10.1016/j.bmcl.2007.02.032 BindingDB Entry DOI: 10.7270/Q28053F2
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50545472 (CHEMBL4642080) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR2 cytoplasmic domain (399-821 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593531 (ASP-5878 \| ASP5878 \| Asp 5878 \| Asp-5878 \| Asp5878) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM25045 (3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of p110alpha by SPA assay				Bioorg Med Chem Lett 17: 2438-42 (2007) Article DOI: 10.1016/j.bmcl.2007.02.032 BindingDB Entry DOI: 10.7270/Q28053F2
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545469 (CHEMBL4635284) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545466 (CHEMBL4645817) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM50559408 (CHEMBL4763773) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged FGFR4 (460 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50559409 (CHEMBL4750924) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged FGFR3 (436 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545472 (CHEMBL4642080) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593528 (CHEMBL5189378) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50545460 (CHEMBL4641667) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR2 cytoplasmic domain (399-821 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50559407 (CHEMBL4791437) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged FGFR3 (436 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
TBA					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 6 (Homo sapiens (Human))	BDBM50243932 (4-[(3,5-Difluorobenzyl)amino]-2-[(4-morpholin-4-yl...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells				Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 6 (Homo sapiens (Human))	BDBM50244256 (4-Benzylamino-2-{[4-(4-methylpiperazin-1-yl)phenyl...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells				Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 6 (Homo sapiens (Human))	BDBM50244258 (4-(benzylamino)-2-(4-morpholinophenylamino)pyrimid...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells				Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 6 (Homo sapiens (Human))	BDBM50244257 (4-Benzylamino-2-[(4-piperazin-1-ylphenyl)amino]-py...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells				Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 6 (Homo sapiens (Human))	BDBM50244331 (4-[(2-Chlorobenzyl)amino]-2-[(4-morpholin-4-ylphen...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells				Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 6 (Homo sapiens (Human))	BDBM50244329 (4-[(2-Methoxybenzyl)amino]-2-[(4-morpholin-4-ylphe...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of STAT6 activation (unknown origin) in FW4 reporter cells				Bioorg Med Chem 16: 6509-21 (2008) Article DOI: 10.1016/j.bmc.2008.05.031 BindingDB Entry DOI: 10.7270/Q2VD6Z7H
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM25118 ((3Z)-4-amino-5-fluoro-3-[5-(4-methylpiperazino)-1,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of FGFR3 (unknown origin) expressed in baculovirus infected insect cells using biotinylated-GGGGQDGKDYIVLPI peptide as substrate incubated...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
Astellas Pharma Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

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