| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
|---|
| Ligand | BDBM347370 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | in vitro assay |
|---|
| IC50 | >7500±n/a nM |
|---|
| Citation |  Markowitz, S; Willson, JK; Posner, B; Ready, J; Zhang, Y; Tai, H; Antczak, M; Gerson, S; Bae, K; Yang, SY; Desai, A Compositions and methods of modulating 15-PGDH activity US Patent US10301320 Publication Date 5/28/2019 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
|---|
| Name: | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] |
|---|
| Synonyms: | 15-PGDH | 15-hydroxyprostaglandin dehydrogenase [NAD+] | HPGD | PGDH1 | PGDH_HUMAN | Prostaglandin dehydrogenase 1 (15-PGDH) | SDR36C1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 28974.46 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P15428 |
|---|
| Residue: | 266 |
|---|
| Sequence: | MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF
IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLD
YMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNA
ICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNG
AIMKITTSKGIHFQDYDTTPFQAKTQ
|
|
|
|---|
| BDBM347370 |
|---|
| n/a |
|---|
| Name | BDBM347370 |
|---|
| Synonyms: | US10301320, ID SW208068 | US10869871, ID # SW208068 | US20230285402, ID # SW208068 | US9789116, SW208068 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H14N2S |
|---|
| Mol. Mass. | 182.286 |
|---|
| SMILES | CCCCSc1ncccc1N |
|---|
| Structure | 
|
|---|
Search and Browse
