| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-6 |
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| Ligand | BDBM29582 |
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| Substrate/Competitor | Caspase-6 Substrate |
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| Meas. Tech. | Enzyme Inhibition Assay |
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| IC50 | 156±n/a nM |
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| Citation |  Chu, W; Rothfuss, J; Chu, Y; Zhou, D; Mach, RH Synthesis and in vitro evaluation of sulfonamide isatin Michael acceptors as small molecule inhibitors of caspase-6. J Med Chem52:2188-91 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Caspase-6 |
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| Name: | Caspase-6 |
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| Synonyms: | Apoptotic protease Mch-2 | CASP-6 | CASP6 | CASP6_HUMAN | Caspase | MCH2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 33312.62 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P55212 |
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| Residue: | 293 |
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| Sequence: | MSSASGLRRGHPAGGEENMTETDAFYKREMFDPAEKYKMDHRRRGIALIFNHERFFWHLT
LPERRGTCADRDNLTRRFSDLGFEVKCFNDLKAEELLLKIHEVSTVSHADADCFVCVFLS
HGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLVGKPKIFIIQACRGNQHDVPVIPLDVVDN
QTEKLDTNITEVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKYG
SSLEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQVPCFASMLTKKLHFFPKSN
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| BDBM29582 |
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| Caspase-6 Substrate |
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| Name: | Caspase-6 Substrate |
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| Synonyms: | N-Acetyl-Val-Glu-Ile-Asp-7-amido-4-methylcoumarin |
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| Type: | Fluorogenic Substrate |
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| Mol. Mass.: | 952.13 |
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| Organism: | n/a |
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| Description: | n/a |
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| Residue: | 9 |
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| Sequence: | |
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