Reaction Details |
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Target | Retinoic acid receptor alpha [200-419] |
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Ligand | BDBM31892 |
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Substrate/Competitor | BDBM31883 |
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Meas. Tech. | Retinoid Competition Binding Assay |
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pH | 7.9±n/a |
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Temperature | 277.15±n/a K |
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Kd | 0.3±n/a nM |
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Citation | Klaholz, BP; Mitschler, A; Moras, D Structural basis for isotype selectivity of the human retinoic acid nuclear receptor. J Mol Biol302:155-70 (2000) [PubMed] Article |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Retinoic acid receptor alpha [200-419] |
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Name: | Retinoic acid receptor alpha [200-419] |
Synonyms: | NR1B1 | Nuclear receptor subfamily 1 group B member 1 | RAR-alpha | RARA | RARA_HUMAN | Retinoic Acid Receptor, alpha |
Type: | Ligand-binding domain |
Mol. Mass.: | 24746.59 |
Organism: | Homo sapiens (Human) |
Description: | P10276[200-419] |
Residue: | 220 |
Sequence: | PALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQIT
LLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPL
EMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLM
KITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEG
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BDBM31892 |
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BDBM31883 |
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Name | BDBM31892 |
Synonyms: | 9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin | alitretinoin |
Type | Small organic molecule |
Emp. Form. | C20H28O2 |
Mol. Mass. | 300.4351 |
SMILES | C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O |c:4| |
Structure |
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